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17 天
植物中KCS6-CER2复合体测定VLCFA链长的结构基础
植物中非常长链脂肪酸(VLCFAs)的链长由KCS6-CER2复合体的结构决定。研究通过冷冻电镜解析了柑橘KCS6-CER2和KCS6-CER2-like1复合体的结构,发现其形成了一个弯曲的疏水延伸通道,通道的疏水性和体积决定了VLCFAs的最大链长(C28至C34)。KCS6催化链延伸至C28,CER2家族 ...
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