A new approach for delivering miniature research tools into the interior of egg cells and embryos has been developed, resolving a major bottleneck to using the gene-editing tool CRISPR-Cas9 in many ...

Crispr Therapeutics, a leader in CRISPR/Cas9 biotechnology, recently received FDA and EMA approval for Casgevy, the first CRISPR/Cas9-based treatment for TDT and SCD. The partnership with Vertex ...

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins are core components of fast-evolving therapeutic gene editing tools. Scientists have used CRISPR ...

A new approach for delivering miniature research tools into the interior of egg cells and embryos has been developed at the Marine Biological Laboratory (MBL), resolving a major bottleneck to using ...

The acorn worm (Saccoglossus kowalevskii) is an important research organism in evolutionary developmental biology and is collected in Woods Hole. Its eggs are very fragile and they typically don’t ...

Scientists introduced CRISPR to the world as a gene-editing tool in summer 2012, when landmark papers from two independent groups demonstrated how the system could be wielded to make cuts in DNA. Now, ...

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In this Peek Behind the Paper, we learn more about a recently published paper by Joaquin Abugattas-Nuñez Del Prado (Leiden University, The Netherlands; Universidad Peruana Cayetano Heredia, Lima, Perú ...

A powerful form of DNA-editing machinery discovered in bacteria might allow us to make much bigger changes to genomes than is currently possible with CRISPR-based techniques. However, it isn’t yet ...