在过去的十年里，免疫检查点阻断疗法（Checkpoint blockade immunotherapies）彻底改变了肿瘤治疗的格局。当我们谈论 PD-1/PD-L1 或 CTLA-4 ...

Immune system activation and activity is regulated through stimulatory or inhibitory ligand-receptor interactions collectively termed immune checkpoints. 1 Stimulatory interactions give the immune ...

Immune checkpoint inhibitors have significantly improved survival for a variety of malignancies over the past decade, but the costs of these medications have barely changed.An investigation into 11 ...

Sacramento Police set up a DUI checkpoint in 2015 in downtown Sacramento. Police said officers would hold a checkpoint Friday, Aug. 23, 2022, near Sacramento State. Stuart Leavenworth Sacramento Bee ...

The California Highway Patrol will be on the lookout for drunk drivers in the Sacramento region — as well as those without proper identification. Officers with the CHP’s South Sacramento area office ...

GameSpot may get a commission from retail offers. The feeling of reaching the peak in Peak is one of satisfaction. The feeling after slipping into poison, falling off a cliff, or overestimating your ...

Discord has launched its own annual user recap called Discord Checkpoint, similar to Spotify Wrapped. The feature summarizes a user's 2025 activity, including messages sent, time in voice chat, and ...

The Stanislaus County Sheriff’s Office says a Halloween night DUI checkpoint in Riverbank led to several arrests and the discovery of two illegally manufactured “ghost” guns. According to a Sheriff’s ...

Discord has followed the lead of platforms like Spotify and created its own version of Spotify Wrapped for its users. Discord is a popular online hangout spot where people can play video games, chat, ...