The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

As people age, they become more prone to blood clotting diseases, when blood cells called platelets clump together when they don't need to and can cause major issues such as strokes and cardiovascular ...

As people age they become more prone to blood clotting diseases, which can be caused when blood platelets clump together. This clumping can lead to strokes and cardiovascular disease. For decades, ...

Hemostasis is a complex system composed of many procoagulant and regulatory pathways. Multiple pathways, such as the intrinsic pathway, platelet activation and the tissue factor pathway, can affect ...

Studies by researchers at Columbia University Irving Medical Center suggest that one of the immune system’s oldest branches, the complement system, and coagulation dysfunction, may be influencing the ...

Coagulation disorders refer to conditions that affect how the body controls blood clotting. This can mean the body forms too many or too few blood clots. Coagulation disorders are usually due to a ...

Researchers have discovered the blood clotting and immune protein pathways that are activated in severe cases of COVID-19 in children, paving the way for earlier diagnosis and more targeted treatments ...

Inflammatory bowel disease, in which the immune system attacks the gut, is a painful chronic condition that affects three million Americans. Rates of IBD are rising, and there’s currently no cure. IBD ...

A DZHK research team at the University Medical Center Mainz has discovered a new signaling pathway of the coagulation system that controls scar formation after a heart attack. If this signaling ...

Disseminated intravascular coagulation (DIC) is a condition that affects your blood’s clotting abilities. It can either set in slowly or happen very suddenly under particular conditions. It’s also ...