编者按：今年以来，siRNA疗法在治疗凝血相关疾病的研究方面取得了重要里程碑进展。RNA干扰（RNAi）机制通过在肝脏细胞中沉默编码凝血因子或天然抗凝物的mRNA，为治疗凝血相关疾病提供了一种全新的治疗模式。基于GalNAc偶联的递送技术，是将治疗性 ...

Medically reviewed by Steffini Stalos, DO Key Takeaways Blood clotting disorders can be inherited or acquired and lead to either excessive bleeding or too much clotting. Hypercoagulable disorders can ...

Superwarfarins represent a class of long‐acting anticoagulant rodenticides that exert their effect through profound inhibition of vitamin K recycling, primarily by targeting vitamin K epoxide ...

For men with hemophilia B, receipt of gene therapy comprising an infusion of etranacogene dezaparvovec results in sustained endogenous factor IX expression and low annualized bleeding rates over five ...

A potentially fatal disorder which causes blood clotting has been linked to a common cold, according to researchers from the University of North Carolina School of Medicine. The team found a ...

Researchers at McMaster University have made a groundbreaking discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite ...

For men with hemophilia B, receipt of gene therapy comprising an infusion of etranacogene dezaparvovec results in sustained endogenous factor IX expression and low annualized bleeding rates over five ...

To help diagnose von Willebrand disease or other bleeding disorders, a doctor will request various blood tests. These tests will measure the presence and activity of certain substances in the blood.

NovoSeven RT is a prescription drug used to treat certain blood clotting disorders, including hemophilia. The drug is given as an intravenous (IV) infusion, which is an injection into a vein over a ...

Sanofi’s Qfitlia and Cablivi approved in China, expanding care for rare diseasesQfitlia, the first antithrombin-lowering therapy for hemophilia, ...