Interleukin cytokines, notably interleukin-22 (IL-22), play multifaceted roles in modulating the immune response. Their dual functionality—balancing protective tissue repair and mediating inflammatory ...

Interleukin-36 (IL-36) cytokines, comprising agonists (IL-36α, IL-36β and IL-36γ) and the receptor antagonist IL-36Ra, represent a pivotal subset of the IL-1 family that orchestrates both innate and ...

In a recent study posted to the medRxiv* preprint server, researchers compared serum cytokine expression among healthy individuals and those with PASC [post-acute sequelae of coronavirus disease 2019 ...

No single definition of cytokine storm or the cytokine release syndrome is widely accepted, and there is disagreement about how these disorders differ from an appropriate inflammatory response. The ...

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection. The receptor can recognize multiple agonists and has been implicated in ...

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated. Relationships are self-held unless noted. I = Immediate Family ...

Cytokines are small, secreted proteins that transmit messages between cells and members of this superfamily include chemokines, growth factors, interleukins, interferons, colony stimulating factors, ...

Researchers have discovered a novel treatment to relieve cytokine release syndrome (CRS), a life-threatening inflammation triggered by a serious infection or severe burn. Treatment with a short-acting ...

Some characteristics of cancer-testis gene expression regulation in colorectal cancer. This is an ASCO Meeting Abstract from the 2019 ASCO Annual Meeting I. This abstract does not include a full text ...

Cytokines such as interleukin-2 have long held great promise as cancer treatments, but they can cause nasty side effects that have limited their use. They’re not very good drugs because they haven’t ...