Recent advances in cellular biology have underscored the central role of the actin cytoskeleton in the regulation of oocyte maturation and fertilisation. Actin filament rearrangements not only ...

Developing tissues require cells to undergo intricate processes to shift into appropriate niches. This requires a functional connection between adhesion-mediating events at the cell surface and a cyto ...

Left: depolymerized actin filaments; right: one hour after treatment to induce repolymerization. More cells presented repolymerized actin filaments in the control group compared with the ASD ...

José Martínez-Hernández, an Ikerbasque researcher in the Neuronal Ubiquitin Pathways group in the Department of Biochemistry and Molecular Biology of the UPV/EHU's Faculty of Science and Technology, ...

Transglutaminases (TGases) are ubiquitous enzymes that take part in a variety of cellular functions. In the pollen tube, cytoplasmic TGases are likely to be involved in the incorporation of primary ...

A researcher has participated in a study describing what it is during the early stages of Alzheimer's that triggers the loss of dynamics and subsequent impairment of the dendritic spines, the ...

SETD2, known for its involvement on gene expression, also can affect functions controlled by the cytoskeleton, such as movement, metastasis and migration, which are very important for cancer cells.

SETD2 is a protein that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When SETD2 is mutated or lost in clear-cell renal cell carcinoma, researchers turned toward ...

SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When researchers discovered that SETD2 is mutated ...

The spatiotemporal balance of surface proteins such as receptors, transporters and adhesion molecules is essential for cellular and tissue homeostasis. One key process to maintain this balance is ...