The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.

A Targeted Methylation–Based Multicancer Early Detection Blood Test Preferentially Detects High-Grade Prostate Cancer While Minimizing Overdiagnosis of Indolent Disease Enzymatic conversion–mediated ...

By cleverly combining new techniques for analysing DNA at the level of individual molecules, we can achieve real breakthroughs in research into ...

A team of researchers from the Case Western Reserve University School of Medicine has developed a new method for target DNA sequence amplification, testing and analysis. This new technique, or ...

Smithsonian researchers used fecal samples to identify specific wild swift foxes. This method allows for non-invasive monitoring, which reduces stress for the animals. Wes Overvold, Smithsonian’s ...

Hospital for Sick Children in Toronto researchers are reporting that targeted RNA sequencing can detect clinically actionable alterations in 87% of tumors and provide decisive findings where DNA-seq ...