RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

A full-size, high-density RNA microchip is about the size of a fingernail and can contain up to 780 000 unique RNA sequences, each occupying a ~14 x 14 μm² area. The presence and the quality of the ...

In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...

While DNA microarrays are already widely used, adapting the technology to RNA microarrays has proved difficult due to the lower stability of RNA. In 2018, the University of Vienna demonstrated how ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

Researchers from the Faculty of Engineering at The University of Hong Kong (HKU) have developed two innovative deep-learning algorithms, ClairS-TO and Clair3-RNA, that significantly advance genetic ...

(Nanowerk News) An international research team led by the University of Vienna has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity.