Desmosomes are intercellular junctions that confer strong cell–cell adhesion. They are found in epithelia and cardiac muscle and are located at the cell membrane, where they act as anchors for ...

Adherens junctions, which are intercellular adhesive complexes that are crucial for maintaining epithelial homeostasis, are downregulated in many cancers to promote tumour progression. However, the ...

Researchers from the group of Eva van Rooij in collaboration with the UMC Utrecht identified a new mutation that leads to the cardiac disease arrhythmogenic cardiomyopathy (ACM). They assessed the ...

An important discovery about how certain cells stick to each other to form tissue has been made by scientists. The team studied how cells in the skin and heart are bound together through structures ...

How does skin hold you in? How do heart cells beat together? Researchers at the University of California, Davis, Department of Biomedical Engineering, are exploring how structures called desmosomes, ...

Structures called desmosomes connect cells to each other and transfer mechanical stress. They are especially important in tissues under continual mechanical stress, such as heart muscle (pictured).

Cell biologists have developed a new method for measuring how mechanical forces in cells are processed. The skin is our largest organ, and, among other things, it provides protection against ...