In the manufacture of solid dosage forms, the rate at which the active pharmaceutical ingredient (API) is dissolved into solvents simulating the digestive tract fluids is determined with dissolution ...

an active pharmaceutical ingredient is the active ingredient contained in a drug and it is the basic material with the desired pharmaceutical properties. Active pharmaceutical ingredients play core ...

Dissolution testing plays an important role throughout the life cycle of a pharmaceutical product, i.e., from evaluating how quickly a compound dissolves into solution in controlled conditions to ...

Improved Pharma, a leader in pharmaceutical research and solid-state chemistry, is pleased to announce a significant upgrade to its analytical capabilities with the installation of a fully automated ...

Dissolution and drug release tests are directly relevant to the safety and efficacy of many common pharmaceutical dosage forms. To achieve reliable and reproducible results, it is important that ...

Advances in dissolution testing equipment are helping to meet user demands to a certain degree; however, more innovation in the space may be necessary for novel therapies, such as biologics.

This paper discusses what causes cross-linking, how cross-linking is addressed with addition of enzymes, and consideration for occasional high results that can be obtained during release testing. A ...