G protein-coupled receptors (GPCRs) represent the largest family of membrane proteins and one of the most successful therapeutic targets in modern medicine, with approximately 34% of FDA-approved ...

Receptor chromatography has emerged as a pivotal tool in the modern bioanalytical and drug discovery landscape. By utilising immobilised receptors on a solid chromatography support, this technique ...

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. An international team of ...

Onfi (clobazam) is a prescription drug used to treat seizures caused by Lennox-Gastaut syndrome. This drug can interact with alcohol, some supplements, and other medications, such as opioids. Onfi is ...

Amylin, a hormone that controls appetite and blood sugar by activating three different receptors in the brain, could be the basis for the next blockbuster obesity drugs. A University of Oklahoma study ...