Emily P. Hyle, Adam D. Lipworth, Theoklis E. Zaoutis, Irving Nachamkin, Neil O. Fishman, Warren B. Bilker, Xiangquin Mao, Ebbing Lautenbach https://www.jstor.org ...

Multidrug-resistant strains of Klebsiella pneumoniae are a problem in many hospitals. In 1999, the molecular epidemiology of K. pneumoniae with extended-spectrum β-lactamases (ESBLs) was studied at 15 ...

The diversity and increasing prevalence of TEM, SHV and CTX-M-type of ESBLs pose serious threat to the clinical use of third-generation cephalosporins for the treatment of severe infections.

The recent study by Tamma and colleagues and another from 2012 [1] provide insight on whether beta-lactam/beta-lactamase-inhibitor combination antibiotics (BLBLIs ...

Anti-infective company VenatoRx Pharmaceuticals has developed injectable and orally bioavailable broad-spectrum antibiotics that could help curb the expansion of antimicrobial resistance. The company ...

Please provide your email address to receive an email when new articles are posted on . Carbapenems were prescribed as targeted therapy in 58.3% of all infections. Highlighting patient populations ...

Please provide your email address to receive an email when new articles are posted on . Using Clinical and Laboratory Standards Institute, or CLSI, revised breakpoints and omitting extended-spectrum ...

Illustration of Enterobacteriaceae bacteria. Individual bacterium are shown as pink rod shapes. The Enterobacteriaceae family contains over a hundred species including Shigella, Klebsiella, Salmonella ...

Among the major problems faced in medicine, resistance to antibiotics is regarded as a singular challenge. The primary focus of our laboratory is to understand the genetic and amino acid sequence ...