Cyclic nucleotide-gated cation channels are cation channels controlled from inside the cell by second messengers cAMP and cGMP. They allow for transit of cations sodium, calcium and potassium across ...

Cyclic nucleotide-gated ion channels have been identified in animals and plants. However, the physiological role of these ion channels in plant cells and in non-receptor cells of animals is still ...

Scientists have revealed how the electrical patterns formed within an embryo initiate a cascade of molecular changes that culminate in the development of cartilage and bone. Prior studies have shown ...

Ion channels are transmembrane proteins specifically involved with the transport of inorganic ions like Na+, K+, Ca2+, or Cl-. Ion channels are “gated”, i.e. they open in response to a specific ...

The study from St. Jude Children's Research Hospital presents a new understanding of how a VGIC, crucial for the communication of neurons and muscle cells, can become unresponsive. Scientists at St.

Scientists now have a better picture of how voltage-gated sodium (Na v) channels interact with certain animal toxins, thanks to structures solved with cryo-electron microscopy. These channels are ...

Ion channels are membrane proteins, which play a principal role in regulating cellular excitability. They are found in virtually all cells, and are of crucial physiological importance. Based on the ...

Most ion channels are very selective about the ions that may or may not pass through them. They may be conductive for potassium ions and non-conductive for sodium ions, or vice versa. However, a ...