This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...

With a rate of mutation 35 percent higher than random chance, this previously unknown weakness could be a major vector for inherited disease.

Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA can be passed down to future generations and are important for how we ...

Most mutations that cause disease by swapping one amino acid out for another do so by making the protein less stable, according to a major study of human protein variants that was published in Nature ...

A new mega-database of half a million mutations may flag new ways of treating genetic disease, scientists say. When you purchase through links on our site, we may earn an affiliate commission. Here’s ...

Unique mutations in the H5N1 strain enhance replication in human cells and cause severe disease in mice. The virus has spread from birds to mammals, including dairy cows, and infected humans, with one ...

Avian influenza viruses typically require several mutations to adapt and spread among humans, but what happens when just one change can increase the risk of becoming a pandemic virus? A recent study ...

The patient in Louisiana who was hospitalized with severe bird flu illness was found to have a mutated version of the virus, the U.S. Centers for Disease Control and Prevention (CDC) announced last ...