University of Navarra (Spain) researchers have developed RNACOREX, a new open-source software capable of identifying gene ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.

Researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation. Researchers have determined ...

Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

A new genome editing tool—minimal versatile genetic perturbation technology (mvGPT)—can achieve simultaneous and orthogonal gene editing and gene regulation in human cells. The coming together of ...

Scientists studying thousands of rats discovered that gut bacteria are shaped by both personal genetics and the genetics of ...

Researchers developed RNACOREX, an open-source tool that maps gene regulation networks by analyzing miRNA–mRNA interactions. Validated across 13 cancer types using TCGA data, the software predicts ...

If something similar occurs in humans, and given growing evidence that the gut microbiome matters for health, genetic influence on human health may be underestimated in large studies; genes may affect ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.