The gonadotropin hormone receptors, including the follicle-stimulating hormone receptor (FSHR) and the luteinizing hormone/choriogonadotropin receptor (LH/CGR), serve as integral mediators of ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) affects approximately 25% of the global population and is typically linked to obesity. Notably, emerging evidence indicates that 12%–20% of ...

Tesamorelin is a synthetic 44–amino acid analog of growth hormone–releasing hormone (GHRH) that has attracted attention outside the experimental domain for its potential as a research tool. This ...

Angiogenesis contributes fundamentally to embryonic development, tissue homeostasis, and wound healing. Basic fibroblast growth factor (FGF2) is recognized as the first proangiogenic molecule ...

Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a ...

Nat Clin Pract Endocrinol Metab. 2006;2(4):220-230. Thyroid-hormone receptors (TRs) that bind DNA regulatory elements mediate thyroid hormone regulation. TRα mRNA mis-sense mutations, and an ...

The canonical Wnt signaling pathway. The left panel (A) demonstrates the activated Wnt signaling cascade, while the right side portrays the inhibited Wnt signaling cascade. Wnt binds to the Fz ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...