Forward genetic studies use meiotic mapping to adduce evidence that a particular mutation, normally induced by a germline mutagen, is causative of a particular phenotype. Particularly in small ...

(Figure 1) Experiments involving cells from different organs of humans and mice exposed to varying radiation doses revealed mutation patterns correlating with exposure levels. (Figure 2) Exposure to 1 ...

The first systematic whole genome sequencing study of how chemotherapy damages healthy tissues has shown that many, but not all, of these agents cause mutations and premature aging of normal blood ...

For nearly 40 years, the Chernobyl exclusion zone (CEZ) has been a laboratory for scientists to study the long-term effects of radiation exposure. One of the ongoing subjects in this unintentional ...

A microscopic flaw in the brain’s cellular scaffolding can shape brain size for life.

What if doctors could look at a person’s DNA and not only spot a harmful mutation, but also predict the kind of disease it may cause—before symptoms fully appear? Scientists at the Icahn School of ...