The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions—as enzymes, transporters, ...

Combined experimental and theoretical tools that include biochemical and molecular biology approaches, genome, transcriptome, and proteome analyses, and comparative methods, have advanced our ...

A team led by scientists at King's College London, in collaboration with national and international partners, has discovered how a specific group of immune cells in the gut—Group 3 Innate Lymphoid ...

Scientists have used light-activated molecular machines to induce cell-to-cell calcium signaling, revealing a powerful new strategy for drug design. This technology could lead to improved treatments ...

More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as "lipoid granules," along with the buildup of amyloid‐beta (amyloid) plaques and tau protein tangles.

In a study published in the Proceedings of the National Academy of Sciences, researchers have revealed that amyloid fibrils formed by necroptosis mediators, RIPK1 and RIPK3, don't just form within ...