Lactate is a byproduct of exercise and metabolism, fueling our brain when oxygen is limited. More recently, scientists have become aware of the many roles it plays in developing our nervous system.

Second autologous stem cell transplantation as a strategy for management of relapsed multiple myeloma. Effect of elevated LDH on survival according to ISS stage (median months).

Lactate is generated in the body as a byproduct, during normal metabolism and exercise. While considered a useless waste product for a long time, recent studies have shown that lactate can be an ...

A meta-analysis of two randomized, double-blind, placebo-controlled, phase III studies in patients (pts) with metastatic colorectal cancer (mCRC) receiving FOLFOX4 and PTK/ZK to determine clinical ...

Background Lactate dehydrogenase (LDH) isoenzymes are required for adenosine triphosphate production, with each of five different isoenzymes having varying proficiencies in anaerobic versus aerobic ...

In clinical practice, lactate is a well-established tool for establishing diagnosis and prognosis in critically ill patients. 1 It can be used to diagnose sepsis and can also help in monitoring ...

Some past studies have shown that the biomarkers PD-1 and PD-L1 are associated with response to ICI treatment in NSCLC as well as PFS and OS. Authors of past studies have also suggested that ...

When runners talk physiology, two terms dominate the conversation: VO2 max and lactate threshold. The two metrics are related but not the same, and they shape performance in different ways. Naturally, ...