Human fingers and toes do not grow outward; instead, they form from within a larger foundational bud, as intervening cells recede to reveal the digits beneath. This is among many processes captured ...

This figure illustrates that TBX4 is crucial for mammalian limb development during the embryonic stage. It activates FGF10 within the mesoderm and interacts with β-catenin in the Wnt pathway, driving ...

During early development, the embryo builds the body's organs by exchanging chemical signals between different cell types. When developing limbs, a thin band of skin cells at the limb’s surface, ...

Scientists have created a spatial atlas of the incredible process of human limb development, including steps that show digits emerging from a bud as cells recede, instead of growing outward. With ...

Fins and limbs and fins into limbs : the historical context, 1840-1940 / Peter J. Bowler -- Skeletal changes in the transition from fins to limbs / Michael I. Coates and Marcello Ruta -- A historical ...

In a new study published in Nature Communications, EPFL researchers shed light on the axolotl's unparalleled limb regeneration abilities, challenging long-held beliefs and offering new insights into ...

It might sound like something out of the X-men but it came from a lab in California: mutant newts that grew perfect limbs after defective appendages were cut off. The findings help science get one ...

Klippel-Trénaunay syndrome (KTS) refers to a condition that impacts the development of blood vessels, soft tissues, and bones. It often presents with characteristic features, such as a red or purple ...

Scleroderma is a rare autoimmune disease involving an overproduction of the protein collagen. Linear scleroderma usually begins as a streak of hardened, waxy, discolored skin on the forehead, an arm, ...