The increased prevalence of obesity worldwide is associated with an epidemic of type 2 diabetes mellitus. It is well established that a tight correlation exists between body adiposity and glucose ...

研究成果以“肝脏糖原合成通过UDPG抑制S1P从而拮抗脂肪生成（Hepatic glycogenesis antagonizes lipogenesis by blocking S1P via UDPG）”为题，于2024年2月16日发表在《科学》（Science）杂志 图 糖原合成拮抗脂肪生成的机制模式图 在国家自然科学基金项目（批准号：82388201）等 ...

Lipogenesis is a term used to describe a process of fatty acid and triglyceride synthesis from glucose or other substrates. This specific biosynthesis takes place predominantly in the liver, while its ...

Lipogenesis is the process involving the synthesis of fatty acids or triglycerides, which is controlled and regulated by a number of factors in the body. The process is stimulated by a diet high in ...

A fascinating new study, published in the prestigious journal Nature Communications, is shedding light on a previously unknown mechanism by which a hormone released from the gut in the hours after ...

Prevalence and influence on outcome of Neuregulin- (NRG1), HER2/neu- and HER3- expression in patients with metastatic colorectal cancer (mCRC) treated with irinotecan-based first-line regimens (FUFIRI ...

The combination of ervogastat plus clesacostat was more effective at resolving metabolic dysfunction-associated steatohepatitis (MASH) without worsening fibrosis in patients with biopsy-confirmed MASH ...

The liver X receptor (LXR) is a nuclear hormone receptor that is one of the most important regulators of cholesterol homeostasis and plays a key role in triglyceride (TG) regulation. Researchers from ...