Lyophilization is a complex operation used to prepare stable pharmaceutical and biopharmaceutical products through freeze-drying. During lyophilization, the water fraction of the product is reduced to ...

The authors describe a comprehensive methodology for establishing functional equivalence among various lyophilizers. Lyophilization or freeze drying of injectable pharmaceuticals is a well-established ...

Freeze drying, lyophilization, and cryodesiccation are all terms used to describe the process of removing water from a sample at low temperature. This low-temperature dehydration process maximizes ...

Lyophilization is emerging as an effective way to prolong the shelf-life of biologics and to ease their refrigeration requirements, but its process development often requires multiple experiments.

The general principle of lyophilization has hardly changed, but significant advances have occurred in process and product attribute understanding. Lyophilization is a well-established technique within ...

UMass Lowell has opened a state-of-the-art lyophilization facility that will help drive innovation and discovery in biopharmaceutical manufacturing in New England and beyond. Called the Lyophilization ...