Lysosomes are dynamic organelles that receive membrane traffic input from the secretory, endocytic, autophagic and phagocytic pathways. They can also fuse with the plasma membrane. Live-cell imaging ...

Ishikawa, Japan - The correct functioning of our cells rests upon the precise orchestration of many complex processes and organelles. Lysosomes—vital cell organelles—are enzyme-filled subunits found ...

Vesicles are small cellular containers. They perform a variety of functions, such as helping to transport materials that an organism needs to survive and recycle waste materials. There are several ...

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes. An organelle is a small structure in a cell that is ...

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes. Lysosomes ...

For the first time, the pathway through which cells repair damaged lysosomes has been observed and described. Lysosomes are the recycling center of a cell, where molecular waste is degraded into the ...

Long recognized as the cell’s recycling depot, a new study has found lysosomes act as signaling hubs that coordinate metabolism and longevity by communicating signals across tissues. According to a ...

A team of researchers led by Osaka University unravel a tangle of pathways involving calcium, lipids, and the degradation of damaged lysosomes that is essential for preventing crystal-induced kidney ...

Tea will be served at 1:45 p.m., immediately preceding the seminar. This seminar will take place at RRL-101 and by Zoom webinar.

Mutations in the progranulin gene cause a form of frontotemporal dementia, most likely because levels of the protein fall in the central nervous system. How this affects brain function is unknown.