Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with limited therapeutic options. Despite ...

Tissue-resident macrophages are present in virtually every organ of the body to execute a variety of vital functions and ensure tissue integrity and functionality. Single-cell RNA sequencing ...

Acute kidney injury (AKI) is associated with a poor prognosis, and no effective treatment has been established to date. Understanding the mechanisms that prevent the progression of AKI is crucial. In ...

Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable ...

Two complementary studies reveal how an insufficient supply of energy in macrophages, key immune cells in artery walls, ...

Our study has shown for the first time that these specialized macrophages function to actively induce dormancy in DCCs." Confirming the importance of alveolar macrophages in keeping DCCs dormant, Dr.

Even its name is a testament to how enigmatic the tingible macrophage has been. Tingible, which means stainable, certainly gives no clues to its functions – but was, at least, one thing that was known ...

Sepsis is a fatal syndrome characterized by life-threatening organ dysfunction originating from a chaotic and unchecked innate immune response to infection. Notably, macrophages are the master ...

Tumors contain macrophages, immune cells capable of fighting cancer, but their function is suppressed by the tumor, ...

Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable to perform their roles properly due to suppression by the tumor.