All cranial placode progenitors arise from a common precursor field anterior to the neural plate, the pre-placodal region (PPR). We showed that transcription factor Zic1, expressed at the anterior ...
Around the time of gastrulation in higher vertebrate embryos, inductive interactions direct cells to form central nervous system (neural plate) or sensory placodes. Grafts of different tissues into ...
The entire inner ear and the neurons that innervate it derive from a simple piece of embryonic ectoderm next to the hindbrain called the otic placode. This ectoderm thickens, invaginates and folds up ...
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