Since the discovery of the double-helical structure of DNA and postulation of the central dogma of molecular biology, stating that the flow of genetic information goes from DNA to RNA to protein, the ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

DNA is the poster child for high-specificity binding. As long as their base sequences match, two complementary strands of DNA can navigate through a sea of biomolecules, find each other, and hold fast ...

为克服上述问题，团队在CircleBase V2中引入了经过优化的打分算法，该算法同时纳入长度标准化与染色体元件密度标准化的双重校正步骤，从而确保最终评分更精准地反映eccDNA本身的功能潜力，而不受其结构特征或所处基因组背景的影响。

5-BrdU（5-溴脱氧尿嘧啶核苷，Bromodeoxyuridine，AbMole，M6348）是一种人工合成的核苷类似物，其结构与胸腺嘧啶相似，仅在嘧啶环的5位碳上由溴原子取代了胸腺嘧啶的甲基基团。这种结构相似性使5-BrdU能够在细胞周期的S期（DNA合成期）通过竞争性机制替代胸腺嘧啶掺入新合成的DNA链中。5-BrdU（BUdR，CAS ...

Growth of Molecular Diagnostic Testing Spurs Demand for Isolation Products The growing interest in molecular diagnostics as well as genomic and gene-expression analysis is accelerating demand for ...

When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE by ...

CRISPR has the power to correct genetic mutations, but current delivery methods are either unsafe or inefficient, keeping the technology from reaching its full medical potential. With the power to ...

As tough as medieval chainmail armor and as soft as a contact lens. This material is not taken from science fiction, it is a ...

When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE by ...

Nucleic acids are long chains of nucleotides found in all living organisms. Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are two common nucleic acids responsible for providing genetic ...