Tandem mass spectrometry is a powerful tool in proteomics. By ionizing peptides and then fragmenting those ions into smaller product ions, researchers can determine the biomolecules’ amino acid ...

The primary rationale for middle-down proteomics is the need for high-confidence proteoform analysis that is also scalable. A proteoform is defined by its full complement of modifications and sequence ...

This is the fourth and final article in the series, describing the characterization of protein-based bio-therapeutics by bottom-up analysis at the peptide level (peptide-mapping analysis). This ...

Bioactive peptides are small protein fragments that promote metabolic health by exerting a positive influence on biological responses within the body. The therapeutic applications of these novel ...

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the virus responsible for the coronavirus disease 2019 (COVID-19), primarily targets respiratory organs, as it reproduces in, ...