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蛋白翻译后修饰(PTM)研究超全指南(上)
据统计,哺乳动物的蛋白质组包含了数百万种独特的蛋白质形态,这种蛋白质的复杂性是由于约25,000个基因的基因组、将潜在的蛋白种类增加到100,000个的转录组、以及丰富的蛋白质翻译后修饰(PTM)。尤其是PTM, 几乎所有蛋白质都会被多个PTM修饰,因此相对于转录 ...
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