News-Medical.Net on MSN

Hidden kinase state enables rapid and repeated protein phosphorylation

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its ...

A short-lived kinase state that's essential for normal cell migration and T-cell function

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...