More than 1,000 bitter-tasting compounds are recognized by a repertoire of 26 membrane proteins called the type-2 taste receptors (TAS2Rs), also known as the bitter taste receptors 1, 2. Our ...
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Kinetic traps explain differences in GPCR drug efficacy
G-protein coupled receptors (GPCRs) are proteins triggered by ligands (protein-binding chemicals) from outside cells to transmit signals inside the cell.
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