The P23H mutation within the rhodopsin gene (RHO) causes rhodopsin misfolding, endoplasmic reticulum (ER) stress, and activates the unfolded protein response (UPR), leading to rod photoreceptor ...

This is a preview. Log in through your library . Abstract We report on preparation of rhodopsin proteoliposomes with the cytoplasmic domain of rhodopsin facing the exterior of the proteoliposomes.

Animals can adapt their ability to see even with extreme changes in temperature, researchers have discovered. The researchers looked deeply into the eyes of catfish living in cold-water streams at ...

Rhodopsin, a pigment of the retina that is responsible for perception of light is also involved in temperature sensation. The work emerged from a collaboration between the laboratory of Andrew Chess, ...

Retinitis pigmentosa is the most prevalent form of congenital blindness. Using a retinitis pigmentosa mouse model, researchers from Ludwig-Maximilians Universitaet (LMU) in Munich have now shown that ...

As many as 40,000 people in Germany suffer from retinitis pigmentosa. This hereditary disorder is characterized by loss of photoreceptors in the retina, and can be caused by mutations in many ...