A new study suggests that one of the most common diabetes treatments may speed type 2 diabetes progression by causing insulin-producing cells to lose their functional identity. Sulphonylureas have bee ...

Researchers have discovered increased levels of of a microRNA in type 2 diabetes, which has a negative effect on insulin secretion. Their experiments on human insulin producing cells in the pancreas ...

“Although the detailed mechanism for the stimulation of intra-islet GLP-1 secretion remains to be elucidated and further studies are required, as far as we know, our present study is the first to ...

Diabetes is a lifelong, chronic health condition caused by abnormalities in the body’s production and use of the hormone insulin. Research has shown that the feel-good hormone, dopamine (DA), plays a ...

Research has shown that dopamine (DA) plays a key role in how the body regulates the production of insulin. Typically, insulin is secreted by beta-cells in the pancreas in response to glucose—a ...

In type 2 diabetes, the body's ability to release insulin is impaired, which leads to high blood glucose levels. Research led ...

A new research paper was published in Aging (Aging-US) Volume 17, Issue 5, on May 1, 2025, titled "Oxytocin modulates insulin and GLP-1 secretion in pancreatic islets." In this study, scientists from ...

Tirzepatide, a drug approved for diabetes and on the fast track for approval as a weight loss therapy, works through a unique ability to activate two different mechanisms the body uses to control ...

When lipid biologist Usha Acharya at the National Cancer Institute (NCI) tinkered with lipid breakdown pathways in Drosophila melanogaster, she observed something intriguing. Blocking a biochemical ...

Insulin glargine (Lantus ®, sanofi-aventis) claims to have a 24-hour duration of action. Is there any advantage to using it twice daily? If so, what patient population might benefit from twice-daily ...