To address the receptor dysfunction associated with several serious neurological diseases, Michaela Jansen, Pharm.D., Ph.D., from the Texas Tech University Health Sciences Center School of Medicine ...

Osaka - Antidepressants treat symptoms of depression by increasing levels of brain signaling molecules (neurotransmitters) such as serotonin, as with the most widely used type of antidepressant, ...

Serotonin reuptake inhibitors (SRIs) are a class of drugs that affect the brain’s serotonin system, and doctors most commonly prescribe them as antidepressants. SRIs increase the levels of serotonin ...

Scientists have identified a novel mode of action for a potential antidepressant that also leads to nerve cell growth in the mouse hippocampus. The activator of a serotonin receptor uses a different ...

The first pharmacologic therapies for the treatment of depression were MAOIs introduced in the mid-1950s (Keller, 2003; Pacher & Kecskemeti, 2004). As mentioned previously, MAOIs inhibit monoamine ...