Second-generation sequencing technologies have replaced array-based technologies and become the default method for genomics and epigenomics analysis. Second-generation sequencing technologies sequence ...

Computational methods are presented for spline smoothing that make it practical to compute smoothing splines of degrees other than just the standard cubic case. Specifically, an order n algorithm is ...

You can use PROC TRANSREG to output to a SAS data set the same smoothing splines that the GPLOT procedure creates. The SMOOTH transformation is a noniterative transformation for smoothing splines. The ...

where belongs to the set of all continuously differentiable functions with square integrable second derivatives, and is a positive constant. Note The computations for a thin-plate smoothing spline are ...