The researchers first reconstituted the soluble AP-4 core complex in vitro and determined its three-dimensional structure using single-particle cryo-EM. The structural data showed that AP-4 is not a ...

Electron diffraction is a powerful analytical technique used to study the atomic structure of materials. It involves the interaction of a beam of electrons with a crystalline sample, resulting in a ...

Coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a significant threat to global public health. As of today, it has caused ...

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...

Keywords: Computer programs. Nonlinear dynamic analyses. Response-history analyses. Seismic isolation. 3-D-BASIS-ME-MB. Superstructures. Models. Multiple isolation-system levels. Viscous dampers.