Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, No. 16 (Aug. 15, 1989), pp. 6121-6125 (5 pages) Incubation of topologically relaxed plasmid DNA with simian ...
A team of physicists working at the intersection of theory and experiment are shedding new light on the “teamwork” of molecular motors—called RNA polymerases (RNAPs)—that mediate DNA transcription.
Tiny robots could serve all kinds of useful functions, but shrinking their actuators has proven challenging. Now researchers at the University of Wollongong (UOW) in Australia have made artificial ...
Supercoiling and looping can transmit mechanical stress along the DNA backbone that can promote the separation of the strands of the double helix at specific distant sites, exposing the DNA bases, ...
The double helix of DNA is one of the most iconic symbols in science. By imitating the structure of this complex genetic molecule we have found a way to make artificial muscle fibers far more powerful ...
A cell has many ways to regulate gene expression, one of which is the structure of the genome itself; active genes have to be accessible to the cellular machinery to be expressed. The DNA in the ...
Picture in your mind a traditional “landline” telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in ...
A team of physicists working at the intersection of theory and experiment are shedding new light on the 'teamwork' of molecular motors -- called RNA polymerases (RNAPs) -- that mediate DNA ...
Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...
The (when stretched) two-meter-long DNA molecule in each human cell is continuously being unpacked and packed again to enable the expression of genetic information. When genes must be accessed for ...
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