A rare inherited disorder, Xeroderma Pigmentosum (XP) is a photosensitive condition characterized by high susceptibility to skin cancers. XP follows the autosomal recessive pattern of inheritance.

XPC protein acts as a sensor to detect various abnormalities in the DNA structure. The faithful repair of DNA is ensured by using the basal transcription factor TFIIH and XPA protein to verify the ...

Affected populations: Xeroderma pigmentosum is a rare genetic disorder that makes people's skin extremely sensitive to the harmful effects of ultraviolet (UV) light. Both males and females can develop ...

CASABLANCA, Morocco (AP) — Determined for her 7-year-old son to attend school despite a life-threatening sensitivity to sunlight, Nadia El Rami stuck a deal with the school’s director: Mustapha would ...

Caren and Dan Mahar can’t stop the sun from shining to save their 12-year-old daughter, but they’ve done everything short of it. Since finding Katie has xeroderma pigmentosum, a rare genetic disorder ...

Our genomic DNA is continuously damaged by endogenous factors such as reactive oxygen species, and also by environmental factors such as ultraviolet light, radiation, and chemicals. Failure to repair ...

Simple everyday pleasures like going for a walk outside or swimming at the beach would be enough to commit twins Thomas and Vincent to “certain death”. The 23-year-olds were born with an incredibly ...