It takes just a few milliseconds: A vesicle, only a few nanometers in size and filled with neurotransmitters, approaches a cell membrane, fuses with it, and releases its chemical messengers into the ...

Figure 1: Binding and unbinding kinetics of l-AP5 on NMDA receptors in outside-out patches. Figure 2: l-AP5 (250 μM) completely inhibited NMDAR-mediated synaptic responses at silent synapses but lost ...

It takes just a few milliseconds: A vesicle, only a few nanometers in size and filled with neurotransmitters, approaches a cell membrane, fuses with it, and releases its chemical messengers into the ...

The brain’s chatter has always been partly out of reach, with electrical spikes easy to record but the chemical whispers ...

HOUSTON – (Jan. 18, 2023) – The sensory organs that allow us to walk, dance and turn our heads without dizziness or loss of balance contain specialized synapses that process signals faster than any ...

Fifty-plus years ago, Julius Axelrod and his colleagues discovered the phenomenona of neurotransmitter inactivation by reuptake into the nerve terminal, a finding that led to the development of ...

A technology called single-molecule imaging has enabled scientists at the University of Maryland to identify the architecture of synapses – the tiny junctions that connect neurons together – and ...

Neurotransmission, or synaptic transmission, corresponds to the movement of signals between neurons, permitting the transmission of information through the proliferation of action potentials. This ...

Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses. Chemical synapses transmit information within the nervous ...