Cannabis is one of the most widely used illicit substances and there is growing interest in the association between cannabis use and psychosis. Delta-9-Tetrahydrocannabinol (Δ-9-THC) the principal ...

Research suggests that risky decision-making is sensitive to neuromodulatory influences acting upon corticolimbic circuitry. However, while other evidence attests to effects of Δ-9 ...

In a recent study published in JAMA Network Open, researchers compare the pharmacokinetics (PK) and pharmacodynamics (PD) of oral Δ9-tetrahydrocannabinol (Δ9-THC)-dominant and cannabidiol ...

New research adds to evidence that a chemical found naturally in cannabis can -- in the right amounts -- lessen the anxiety-inducing effects of tetrahydrocannabinol (THC), the primary psychoactive ...

In a recent review published in Cannabis and Cannabinoid Research, researchers reviewed studies on the probable conversion of orally administered cannabidiol (CBD) to delta9-tetrahydrocannabinol ...

Tetrahydrocannabinol (THC) and tetrahydrocannabivarin (THCV) are both cannabinoids which, if present in high enough doses, can interact with the body’s endocannabinoid receptors to induce psychoactive ...

An ingenious set of experiments has teased apart the mind-altering and pain-relieving effects of the main component of cannabis. This could open the way to cannabis-like drugs that provide pain relief ...