眼科疾病治疗中的新型基因编辑载体开发与青光眼模型构建。脂质纳米颗粒（LNPs）通过系统评估证明SM102配方在活体小鼠中能特异性靶向小梁网（TM），通过CRISPR-Cas9技术成功敲除Mgp基因，诱导眼压升高和视网膜病理改变，模拟开角型青光眼特征，且具有重复给药 ...

Purpose To analyse high-molecular-weight matrix glycoproteins in trabecular meshwork, cornea and sclera using SDS/PAGE and immuno- and lectin blotting. Method Extracts of normal trabecular meshwork ...

Augmentation of aqueous outflow is the favored strategy to lower IOP in glaucoma surgery. Traditionally, outflow is directed through the sclera into the subconjunctival space with subsequent bleb ...

Please provide your email address to receive an email when new articles are posted on . NEW ORLEANS — The combination of a custom gonioscopy lens and a commercially available OCT allowed researchers ...

The research team includes (from left) Kaitlyn Sapoznik, Thomas Gast, Brett King and Stephen Burns of the Indiana University School of Optometry. (Courtesy: James Brosher, Indiana University) ...

The left image shows the trabecular meshwork as it can be seen in a doctor's office. The right image shows a portion of the same part of the eye in much greater detail using methods developed at IU.