β-arrestin, a protein known to regulate the signalling, trafficking and degradation of mammalian seven-transmembrane-spanning receptors, has now been identified as a regulator of ubiquitination and ...

This is a preview. Log in through your library . Abstract We have investigated the topology of the α and δ subunits of the nicotinic acetylcholine receptor (AChR) from mammalian muscle synthesized in ...

A crucial step in preclinical drug development is the confirmation of the novel therapeutic molecule's specific binding to the targeted protein. Transmembrane proteins (TPs) like ion channels, ...