The catalytic enantioselective synthesis of densely functionalized organic molecules that contain all-carbon quaternary stereocentres is a challenge to modern chemical methodology. The catalytically ...

Figure 1: Positioning and stabilization of enolate anions on π-acidic surfaces.

Now, Baran and DeMartino demonstrate it's possible for intermolecular cross-coupling of different types of enolates, such as a lactam and a ketone (shown, linked by red bond), via enolate oxidation ...